SANTA CLARA, Calif. -- Down big, kept his poise on the road while struggled in prime time.Cutler pa sed for three fourth-quarter touchdowns after much of Chicago's starting defense went down, and the beat the 28-20 Sunday night to spoil their Levi's Stadium debut."We just kept plugging, we knew we had some good stuff," Cutler said. "We just had to figure them out."Cutler threw three TD pa ses to , two in the wild fourth quarter, as Chicago erased a 13-point deficit and quieted the sellout crowd. Cutler threw for two scores in a 27-second span early in the final period, aided by the gutsy play of a backup cornerback. made two late interceptions for the depleted Chicago secondary, and the first set up the go-ahead score."Just coming in here, working hard, it was a team win," said Fuller, the ' first-round pick in this year's draft. "We are thankful for that and will keep on building."Kaepernick was hit with an unsportsmanlike conduct penalty for "inappropriate language" following Fuller's first big play. That gave the first-and-goal on the 3, and Cutler threw a 3-yard TD pa s to as the went ahead 21 Zay Flowers Jersey -20.Kaepernick threw three interceptions in all, lost a fumble and his cool, a far cry from his breakout start on the Monday night stage nearly two years ago in a rout of the . Cutler sat out that night with a concu sion.A sloppy game filled with 26 penalties - 16 by the Niners - and a crazy collapse overshadowed the fanfare of the regular-season debut for the sparkling $1.2 billion stadium.The (1-1), in a stretch with six of eight games on the road, go home with some serious momentum despite injuries on both sides of the ball.Five key defenders are hurt: cornerbacks (quadriceps) and (triceps), defensive end (foot), safety (shoulder) and defensive tackle (concu sion).The (1-1) had a 17-7 halftime lead, but mi sed an opportunity to grab an early lead in the NFC West after the defending champion lost earlier in the day at San Diego. caught a touchdown pa s on his 27th birthday and ran for a score but also had his 54-yard TD burst negated by 's costly holding penalty.Cutler helped the get on the board with a 25-yard run late in the first half. He took a jarring hit from with 56 seconds remaining, but stayed in the game and threw a 17-yard touchdown pa s to Marshall, who made a leaping, one-handed catch to pull the ball into his body as he fell into the end zone.What a way for Chicago to forget that bitter 23-20 overtime lo s to the at home in Week 1.San Francisco didn't give the ball away once in a season-opening win at Dallas.In the first half, the outgained Chicago 197-93 and out-penalized the 10-7 for 85 lost yards. The much-scrutinized field featured visible chunks of loose sod after new gra s was laid for a third time since April.Kaepernick made his first career start against the nearly two years ago, and then held onto the No. 1 job over . Cutler didn't face the during a November 2012 Monday night game at Candlestick Park.A concu sion to now- QB Smith thrust Kaepernick into the spotlight that night, and he threw for 243 yards and two touchdowns as the Niners pounded the 32-7.The were embarra sed at home for the second time in a month. They lost 34-0 in a rout by Denver in the first preseason game in the new stadium.Chicago's patchwork offensive line looked shaky early with center and left guard each sidelined by ankle injuries.San Francisco tight ends (knee) and (ankle) were hurt as the lost a home opener for the first time under fourth-year coach .Copyright 2014 by The A sociated Pre s Jeremy Lucien Jersey